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Mark Rosenberg, M.D., completed his undergraduate studies at the University of Pennsylvania before earning his medical degree from the Georgetown University School of Medicine. He completed his residency in emergency medicine at Brooke Army Medical Center and subsequently served as Assistant Chief of Emergency Medicine at Walter Reed Army Medical Center. During his tenure there, Dr. Rosenberg also acted as a consultant on the management of drug toxicities and overdoses. He left military service in 1996 with the rank of Major. While in residency, he was honored as both Resident of the Year and Teacher of the Year, and he continued teaching during his time at Walter Reed.

In 2004, Dr. Rosenberg diagnosed his mother with metastatic lung cancer, an experience that redirected his professional focus. He began researching therapies targeting cancer stem cells and later founded a pharmaceutical company that ultimately merged with a Harvard spinout. More recently, he was awarded a patent for developing an extracorporeal filtration device designed to capture and eliminate circulating tumor clusters.

Dr. Rosenberg has also served for more than 20 years as a board member and consultant to the American Academy of Anti-Aging Medicine. He currently practices internal medicine, longevity medicine, and integrative oncology.

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